Rhupus Syndrome: An Overlap with Renal Complications

Rhupus Syndrome: An Overlap with Renal Complications

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Rhupus syndrome is a rare condition of fr9967 overlap of Rheumatoid Arthritis (RA) and Systemic Lupus Erythematosus (SLE) presenting with erosive polyarthritis and symptoms of SLE.It occasionally has renal involvement as its complication makes the diagnosis more difficult.Here the authors present a case of a 13-year-old female with severe arthritis, which gradually progressed into lupus nephritis with the presence of specific autoantibodies confirming the climax blueberry cross pollination diagnosis of Rhupus.The child was managed with disease modifying anti-rheumatic drug (hydroxychloroquine), immunosuppressants (mycophenolate mofetil), steroid (prednisolone) and calcium channel blocker (amlodipine).

Accurate diagnosis is the key for early detection since Rhupus is a very rare disorder with very limited reported cases.